Aids in better absorption of Calcium: The major function of Cholecalciferol is to optimize intestinal calcium and phosphorus absorption for proper formation of the bone mineral matrix. Calcium is transported across the intestine by a paracellular or transcellular pathway. Optimal Cholecalciferol levels are necessary to increase the efficiency of calcium absorption. Without adequate Cholecalciferol, the body absorbs no (1)* more than 10% to 15% ofdietary calcium. In the Cholecalciferol–sufficient state, the intestinal calcium absorption increases to 30% to 40% .
Promotes bone health: Cholecalciferol plays an important role in regulation of calcium and maintenance of phosphorus levels in the blood, (2)* which is required to maintain healthy bones . Deficiency of Cholecalciferol can cause bone loss that leads to osteoporosis and fractures, (3)* demineralisation which eventually leads to osteomalacia and muscle weakness causing fractures .
Promotes Teeth Health: Teeth are nothing but mineralized organs which are enclosed by alveolar bone and are developed by three different hard tissues such as dentin, enamel, and cementum. The mineralization process of teeth happens similar to the type of skeletal mineralization, and if in case still the mineral metabolism gets hindered then it will result in failures just like those which happen in the bone tissue. Cholecalciferol has been playing a predominant vital part in the tooth and bone mineralization, and it can result in rachitic (4)* tooth when the levels get unregulated .
Improves muscle health: Studies show significant effects ofvitamin D supplementation on plasma 25-hydroxyvitmin D (25OHD) levels. Alot of other studies showed beneficial effects of vitamin D consumption on muscle function in terms of an improved muscle strength, a reduced body sway. Several in vivo and in vitro studies have shown physiological, histological and electrophysiological changes in severe vitamin D deficiency, supporting an effect ofvitamin D on muscle health. Binding ofvitamin D to its receptors stimulates uptake ofinorganic phosphate (5)* used for the formation ofenergy-rich phosphate compounds necessary for muscle cell contractility .
Improves Immunity: Cholecalciferol effects on the innate immune system are predominantly through the toll-like receptors and on the (6)* adaptive immune system through T-cell differentiation, particularly the Thelper cell (TH) .
Cholecalciferol IP(In Nano Droplet form) - 60000 IU
